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Characterization of the CoQ-Synthome Proteins and Binding Partners, Their Phosphorylation Status, and Alternative Splicing and Regulation in Saccharomyces cerevisiae
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Awad, Agape Mamdouh. |
| 단체저자명 | University of California, Los Angeles. Biochemistry & Molecular Biology 0114. |
| 서명/저자사항 | Characterization of the CoQ-Synthome Proteins and Binding Partners, Their Phosphorylation Status, and Alternative Splicing and Regulation in Saccharomyces cerevisiae. |
| 발행사항 | [S.l.] : University of California, Los Angeles., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 134 p. |
| 소장본 주기 | School code: 0031. |
| ISBN | 9780438081123 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Catherine F. Clarke. |
| 요약 | Coenzyme Q (also termed ubiquinone or Q) is an electron carrier in the mitochondrial respiratory chain that functions as an essential component in energy metabolism processes. Q transfers electrons from NADH and succinate to cytochrome c, a heme |
| 요약 | Saccharomyces cerevisiae (baker's yeast) serves as an excellent model for studies on Q because of its powerful molecular genetics and its close homology to human Q biosynthesis and function. Q biosynthesis in S. cerevisiae (which makes Q6 with s |
| 요약 | Chapter 2 investigates potential additional protein partners of the CoQ-Synthome. Via tandem affinity purification and proteomic and mass spectrometry analysis---facilitated by dualtagged Coq polypeptides---YLR290C was identified as a CoQ-Syntho |
| 요약 | Given the findings contained in Chapter 2 related to the association of Coq6 with the putative kinase of the system, Coq8, the question now remains whether Coq6 is a phosphorylated Coq polypeptide, similar to Coq3, Coq5, and Coq7. Chapter 3 furt |
| 요약 | Chapter 4 details the extensive story of alternative splicing in yeast, and in particular, as it relates to the Coenzyme Q biosynthetic pathway. Previous findings from another collaborating laboratory showed that Coq7 contained several phosphory |
| 일반주제명 | Biochemistry. Aging. Genetics. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-11B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999127 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00028436 | 574 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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