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The Roles of Set-9 and Set-26 in Longevity, Germline Function and RNAi Pathway
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Wang, Wenke. |
| 단체저자명 | Cornell University. Biology. |
| 서명/저자사항 | The Roles of Set-9 and Set-26 in Longevity, Germline Function and RNAi Pathway. |
| 발행사항 | [S.l.] : Cornell University., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 208 p. |
| 소장본 주기 | School code: 0058. |
| ISBN | 9780438027121 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Siu S. Lee. |
| 요약 | Aging, germline function and RNA interference are three distinct biological processes that associate with alterations in epigenetic state, including histone modifications. Our lab discovered two highly homologous SET domain containing genes, set |
| 요약 | My work found that SET-26 but not SET-9 plays an important role in lifespan regulation. Endogenous SET-26 is broadly expressed while SET-9 is only detectable in the germline. Specifically, somatically expressed SET-26 is implicated in lifespan d |
| 요약 | SET-9 and SET-26 are putative homologs of the human protein Mixed Lineage Leukemia 5 (hMLL5), which plays an important role in regulating hematopoietic homeostasis, cell cycle and survival. However, the molecular basis underlying hMLL5 activity |
| 일반주제명 | Molecular biology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-10B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14998294 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00027715 | 574 | 가야대학교// | 대출가능 |
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