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Breast Cancer Detection: From Tumor-specific Nanoparticles to Cell Mechanics
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Hu, Jingjie. |
| 단체저자명 | Princeton University. Mechanical and Aerospace Engineering. |
| 서명/저자사항 | Breast Cancer Detection: From Tumor-specific Nanoparticles to Cell Mechanics. |
| 발행사항 | [S.l.] : Princeton University., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 171 p. |
| 소장본 주기 | School code: 0181. |
| ISBN | 9780438047860 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Winston O. Soboyejo. |
| 요약 | This thesis presents combined experimental and theoretical studies of cancer cell mechanics and peptide-enhanced nanoparticle entry/adhesion to triple negative breast cancer (TNBC) cells. |
| 요약 | The adhesive interaction between functionalized nanoparticles and biological cells is critical for effective cancer targeting. A combination of atomic force microscopy (AFM) and simulation approaches are used to evaluate the adhesion and molecul |
| 요약 | To investigate Triptorelin-MNP cluster entry mechanism and cellular uptake efficacy, thermodynamics and kinetics modeling and optical/confocal fluorescence microscopy are used to show that Triptorelin ligands enhance the uptake of Triptorelin-MN |
| 요약 | Finally, a cell mechanics approach is explored for TNBC cell detection. This involves the use of a shear assay technique, in parallel with digital image correlation and a Maxwell model for the measurements of viscoelastic properties as effective |
| 일반주제명 | Materials science. Bioengineering. Nanotechnology. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International79-10B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14998171 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00027589 | 620.11 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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