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Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2

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개인저자Turton, Keren B.
단체저자명The University of Wisconsin - Madison. Biomolecular Chemistry.
서명/저자사항Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2.
발행사항[S.l.] : The University of Wisconsin - Madison., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항263 p.
소장본 주기School code: 0262.
ISBN9780438271593
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Deane F. Mosher.
요약Following interleukin-5 stimulation, eosinophils rapidly become acorn-shaped. The bi-lobed nucleus is propelled to the cone of the acorn, termed the "nucleopod". By integrating eosinophil immunostaining with (phospho)proteomics data
요약Signal transducer and activator of transcription 3 (STAT3) is an important regulator of transcription in activated leukocytes. An unexpected STAT3 isoform peptide, lacking a single residue (Ser701) led to the questions, what are the relative pro
요약We describe the "LOCGEFs", a set of leukocyte-specific spliceforms of ARHGEF18, a guanine nucleotide exchange factor. These proteins were discovered because the proteomics dataset included peptides mapping to a protein annotated as LOC100996504.
요약Nance-Horan Syndrome-like protein 2 (NHSL2) was one of the most profoundly altered proteins after IL5 treatment: within 5 minutes, the fold-phosphorylation at 4 sites increased dramatically. Nearly nothing is published about this protein, so we
일반주제명Biochemistry.
언어영어
기본자료 저록Dissertation Abstracts International79-12B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14999730

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