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Manipulating Neuronal Dynamics in the Primate Brain Using Optogenetic Stimulation

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개인저자Shewcraft, Ryan Allen.
단체저자명New York University. Neural Science.
서명/저자사항Manipulating Neuronal Dynamics in the Primate Brain Using Optogenetic Stimulation.
발행사항[S.l.] : New York University., 2018
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2018
형태사항195 p.
소장본 주기School code: 0146.
ISBN9780438170414
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Bijan A. Pesaran.
요약Understanding how different brain areas interact is important to understanding how brain networks support flexible behavior. Brain networks are often studied by analyzing correlations in activity between brain areas. The presence and strength of
요약In the first part of the work, I studied the dynamics of local neural interactions. I found that the dynamics of local responses to optogenetic stimulation are non-linearly dependent and reveal the attenuation of neural responses at frequencies
요약In the second part of the work, I investigated parietal-frontal neuronal coupling - the efficacy of synaptic input from parietal cortex on frontal cortical neurons. To measure neuronal coupling, I optogenetically-stimulated neurons in the poster
요약In the third part of the work, I analyzed neural interactions across large-scale, brain networks involving multiple areas by combining optogenetic stimulation with simultaneous fMRI recordings. Optogenetic stimulation in the frontal cortex gener
요약These studies show how measuring the dynamics of neural circuits during causal manipulations can reveal the organization of interactions across local and distributed brain networks. I will discuss implications of these findings for the control o
일반주제명Neurosciences.
언어영어
기본자료 저록Dissertation Abstracts International79-12B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14996728

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