자료유형 | E-Book |
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개인저자 | Dolor, Aaron. |
단체저자명 | University of California, San Francisco. Pharmaceutical Sciences and Pharmacogenomics. |
서명/저자사항 | Modifications of the Target or Therapeutic for Improved Drug Delivery. |
발행사항 | [S.l.] : University of California, San Francisco., 2018 |
발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
형태사항 | 159 p. |
소장본 주기 | School code: 0034. |
ISBN | 9780438250512 |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Francis C. Szoka. |
요약 | Liposomes featuring a lipid bilayer surrounding an aqueous core, have been utilized as carriers for drugs and macromolecules since the 1970s. Liposomal drug encapsulation improves the pharmacokinetics, biodistribution, and pharmacodynamics of dr |
요약 | Despite the longevity, further clinical adoption of liposomes and nanomaterials has been limited due to a lack of effective targeting, undesired drug release kinetics, or inadequate drug penetration. In this dissertation, we present strategies t |
요약 | Subsequently, we turned our focus to approaches to make the target tissue more receptive to drug delivery. We communicate procedures to recombinantly purify matrix metalloproteinase-8 (MMP-8), a key enzyme for tissue remodeling. We demonstrate m |
일반주제명 | Pharmaceutical sciences. |
언어 | 영어 |
기본자료 저록 | Dissertation Abstracts International79-12B(E). Dissertation Abstract International |
대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999338 |
인쇄
No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
---|---|---|---|---|---|---|---|---|
1 | WE00026401 | 615 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |