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Development of Trojan Horse Dimeric Inhibitors of P-Glycoprotein to Target HIV Reservoirs in the Brain
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Agrawal, Neha. |
| 단체저자명 | Purdue University. Chemistry. |
| 서명/저자사항 | Development of Trojan Horse Dimeric Inhibitors of P-Glycoprotein to Target HIV Reservoirs in the Brain. |
| 발행사항 | [S.l.] : Purdue University., 2018 |
| 발행사항 | Ann Arbor : ProQuest Dissertations & Theses, 2018 |
| 형태사항 | 210 p. |
| 소장본 주기 | School code: 0183. |
| ISBN | 9780438361713 |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Jean A. Chmielewski. |
| 요약 | HIV/AIDS has emerged as an incredibly serious infectious disease. The complete eradication of HIV is hindered by virus reservoir formation in the host. Some of the locations of these reservoirs include the central nervous system (CNS), resting m |
| 요약 | All the TH heterodimeric were found to inhibit P-gp mediated efflux of fluorescent substrates in T-cells as well as model blood-brain barrier cell lines. Two TH heterodimeric were found to inhibit HIV-1 replication in 12D7 cells most effectively |
| 일반주제명 | Chemistry. Organic chemistry. Biochemistry. |
| 언어 | 영어 |
| 기본자료 저록 | Dissertation Abstracts International80-01B(E). Dissertation Abstract International |
| 대출바로가기 | http://www.riss.kr/pdu/ddodLink.do?id=T14999968 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00024703 | DP 540 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출불가(별치) |
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