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Investigation of Interaction Between Peptide and Lipid Bilayer by Molecular Dynamics Simulation

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개인저자Xiang, Ning.
단체저자명Purdue University. Agricultural and Biological Engineering.
서명/저자사항Investigation of Interaction Between Peptide and Lipid Bilayer by Molecular Dynamics Simulation.
발행사항[S.l.] : Purdue University., 2017
발행사항Ann Arbor : ProQuest Dissertations & Theses, 2017
형태사항152 p.
소장본 주기School code: 0183.
ISBN9780355613582
일반주기 Source: Dissertation Abstracts International, Volume: 79-07(E), Section: B.
Adviser: Ganesan Narsimhan.
이용제한사항This item is not available from ProQuest Dissertations & Theses.
요약Antimicrobial peptides (AMPs) inactivate microbial cells through pore formation in cell membrane. Because of their different mode of action compared to antibiotics, AMPs can be effectively used to combat drug resistant bacteria in human health.
요약The effects of (i) number of total and net charges, (ii) hydrophobicity (iii) hydrophobic moment and (iv) helicity of peptides from soy protein on their ability to bind to lipid bilayer and their transmembrane aggregates to form pores were inves
요약MD simulation was also employed to investigation interaction between amyloid beta (Abeta) peptide and lipid bilayer. Some amyloid-related proteins/peptides are involved in aggregation and pore formation in phospholipid membranes (cell membranes)
일반주제명Agricultural engineering.
Food science.
Computational chemistry.
언어영어
기본자료 저록Dissertation Abstracts International79-07B(E).
Dissertation Abstract International
대출바로가기http://www.riss.kr/pdu/ddodLink.do?id=T14996789

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