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Hallelujah moments : tales of drug discovery / [electronic resource]
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| 자료유형 | E-Book |
|---|---|
| 개인저자 | Cordes, Eugene H., author. |
| 서명/저자사항 | Hallelujah moments :tales of drug discovery /Eugene H. Cordes.[electronic resource] |
| 판사항 | Second edition. |
| 발행사항 | New York, NY : Oxford University Press, 2020. |
| 형태사항 | 1 online resource (xvi, 310 pages) : illustrations |
| 소장본 주기 | WorldCat record variable field(s) change: 650 |
| ISBN | 9780190080488 0190080485 9780190080464 0190080477 9780190080471 0190080469 |
| 서지주기 | Includes bibliographical references and index. |
| 내용주기 | Preface -- Previous Edition Preface -- Acknowledgments -- 1. Seduced by drug discovery -- 2. Proscar and Propecia: the Gary and Jerry show -- 3. Basic research, snake venoms, and ACE inhibitors: Ondetti, Cushman, and Patchett -- 4. HIV protease inhibitors: weapons in the war against HIV/AIDS -- 5. Statins: protection against heart attacks and strokes -- hallelujah! -- 6. The perils of Primaxin -- 7. The discovery of taxol: Wall, Horwitz, Holton -- 8. Avermectins: molecules of life battle parasites -- 9. Fludalanine: nice try but no hallelujah -- 10. Diabetes breakthroughs: Thornberry and Weber -- 11. Take it off! Take it all off! Drugs for weight reduction -- 12. The conquest of hepatitis C: telaprevir and beyond -- Appendix A: The small molecules of life: some basics of chemistry -- Appendix B: The basics of protein structure -- Appendix C: Proteins perform multiple functions: enzymes, receptors, ion channels -- Appendix D: The basics of drug discovery and development -- Appendix E: Structures of key molecules -- Notes -- Index. |
| 요약 | "This work provides eleven stories of drug discovery and features the scientists who made them. The outcome of the discovery work has provided novel therapies in cancer, cardiovascular medicine, antibacterial and antiviral infectious diseases, parasitic diseases, metabolic diseases, and weight control. Each story begins with the basic biomedical science that revealed the pathway to effective drug therapy and continues with the step-by-step process that leads from insight to a product in clinical practice meeting a defined medical need. The tales feature creative problem solving by clever and dedicated scientists as they overcame roadblocks to success., hallelujah moments. Each drug discovery story reflects the interface between basic science, medicine, and drug discovery. Embedded in these tales are the societal and medical environments in which drug discovery takes place, the discovery of agents to treat HIV/AIDS, for example. Finally, a series of appendices provides basic chemical background for non-scientists"-- |
| 일반주제명 | Drug development. Developmental pharmacology. Drugs -- Research. Developmental pharmacology. Drug development. |
| 언어 | 영어 |
| 기타형태 저록 | Print version:Cordes, Eugene H.Hallelujah moments.Second edition.New York, NY : Oxford University Press, 20209780190080457 |
| 대출바로가기 | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2434578 |
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| No. | 등록번호 | 청구기호 | 소장처 | 도서상태 | 반납예정일 | 예약 | 서비스 | 매체정보 |
|---|---|---|---|---|---|---|---|---|
| 1 | WE00019162 | 615.1/9 | 가야대학교/전자책서버(컴퓨터서버)/ | 대출가능 |
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